Jian-Xing Ma Selected Research

Retinal Neovascularization

12/2021	Therapeutic Effects of Fenofibrate Nano-Emulsion Eye Drops on Retinal Vascular Leakage and Neovascularization.
1/2020	Detection and Quantification of Retinal Neovascularization Using BrdU Incorporation.
1/2020	PPARα-Dependent Effects of Palmitoylethanolamide Against Retinal Neovascularization and Fibrosis.
10/2017	Therapeutic Effects of a Novel Agonist of Peroxisome Proliferator-Activated Receptor Alpha for the Treatment of Diabetic Retinopathy.
1/2016	sFlt Multivalent Conjugates Inhibit Angiogenesis and Improve Half-Life In Vivo.
4/2015	MicroRNA-184 modulates canonical Wnt signaling through the regulation of frizzled-7 expression in the retina with ischemia-induced neovascularization.
12/2013	An update on the molecular actions of fenofibrate and its clinical effects on diabetic retinopathy and other microvascular end points in patients with diabetes.
11/2013	Regulation of endothelial progenitor cell release by Wnt signaling in bone marrow.
11/2012	Therapeutic potential of a monoclonal antibody blocking the Wnt pathway in diabetic retinopathy.
1/2012	Dual inhibition of plasminogen kringle 5 on angiogenesis and chemotaxis suppresses tumor metastasis by targeting HIF-1α pathway.

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Jian-Xing Ma Research Topics

Disease

25	Diabetic Retinopathy (Retinopathy, Diabetic) 12/2021 - 02/2006
20	Inflammation (Inflammations) 01/2021 - 11/2005
13	Retinal Neovascularization 12/2021 - 02/2006
11	Macular Degeneration (Age-Related Maculopathy) 12/2021 - 01/2007
9	Retinal Degeneration 01/2022 - 08/2006
8	Neoplasms (Cancer) 01/2021 - 04/2006
8	Ischemia 01/2020 - 03/2005
7	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 01/2020 - 09/2010
7	Type 2 Diabetes Mellitus (MODY) 01/2020 - 10/2008
7	Diabetic Nephropathies (Diabetic Nephropathy) 01/2020 - 01/2005
6	Choroidal Neovascularization 12/2021 - 11/2007
6	Leukostasis 01/2020 - 11/2012
6	Corneal Neovascularization 01/2018 - 11/2005
5	Fibrosis (Cirrhosis) 12/2021 - 02/2006
5	Pathologic Neovascularization 01/2020 - 04/2014
5	Burns 01/2018 - 11/2005
4	Retinal Diseases 01/2020 - 01/2007
4	Hypoxia (Hypoxemia) 01/2020 - 12/2007
3	Glioblastoma (Glioblastoma Multiforme) 11/2020 - 01/2019
3	Chronic Renal Insufficiency 01/2020 - 01/2019
2	Eye Diseases (Eye Disease) 01/2021 - 09/2014
2	Uveitis 01/2021 - 01/2020
2	Gliosis 01/2020 - 01/2016
2	Albuminuria 01/2020 - 02/2006
2	Diabetes Complications 01/2020 - 05/2019
2	Mitochondrial Diseases (Mitochondrial Disease) 01/2019 - 06/2008
2	Neuroinflammatory Diseases 08/2018 - 01/2016
2	Myopia 09/2016 - 01/2015
2	Hyperglycemia 01/2016 - 01/2005
2	Stargardt Disease 01/2013 - 09/2011
2	Hepatocellular Carcinoma (Hepatoma) 01/2012 - 04/2006
1	Macular Edema 12/2021
1	Autoimmune Diseases (Autoimmune Disease) 01/2021
1	Dry Eye Syndromes (Dry Eye Syndrome) 01/2021

Drug/Important Bio-Agent (IBA)

36	Retinaldehyde (Retinal)IBA 01/2022 - 03/2005
13	Therapeutic UsesIBA 12/2021 - 11/2005
10	Proteins (Proteins, Gene)FDA Link 01/2020 - 06/2006
9	Fenofibrate (CiL)FDA LinkGeneric 12/2021 - 12/2013
8	CateninsIBA 11/2020 - 11/2012
8	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2019 - 12/2007
7	Oxygen (Dioxygen)IBA 01/2020 - 09/2012
6	pigment epithelium-derived factorIBA 05/2014 - 01/2005
5	kallistatinIBA 01/2021 - 09/2010
5	AlkaliesIBA 01/2018 - 11/2005
4	Peroxisome Proliferator-Activated Receptors (PPAR)IBA 01/2021 - 10/2014
4	Peptides (Polypeptides)IBA 01/2021 - 01/2012
4	Pharmaceutical PreparationsIBA 01/2020 - 01/2007
4	oxidized low density lipoproteinIBA 01/2016 - 06/2008
4	LipidsIBA 10/2014 - 09/2010
3	VLDL LipoproteinsIBA 12/2021 - 11/2007
3	Kallikreins (Kallikrein)IBA 01/2021 - 12/2007
3	Carrier Proteins (Binding Protein)IBA 01/2021 - 12/2007
3	PPAR alphaIBA 01/2020 - 10/2017
3	Retinal Pigments (Pigments, Visual)IBA 01/2020 - 01/2015
3	Serine Proteinase Inhibitors (Serine Protease Inhibitors)IBA 01/2020 - 06/2014
3	erucylphosphocholineIBA 10/2019 - 01/2012
3	Glucose (Dextrose)FDA LinkGeneric 05/2019 - 01/2005
3	RetinoidsIBA 07/2018 - 01/2017
2	Ophthalmic Solutions (Eye Drops)IBA 12/2021 - 09/2010
2	Rhodopsin (Visual Purple)IBA 01/2021 - 10/2017
2	DNA (Deoxyribonucleic Acid)IBA 01/2020 - 09/2014
2	CreatinineIBA 10/2019 - 09/2010
2	AlbuminsIBA 10/2019 - 09/2010
2	Streptozocin (Streptozotocin)FDA Link 01/2019 - 11/2012
2	Intercellular Adhesion Molecule-1 (Intercellular Adhesion Molecule 1)IBA 01/2019 - 12/2012
2	Monoclonal AntibodiesIBA 01/2018 - 11/2012
2	Retinol-Binding Proteins (Retinoid Binding Proteins)IBA 01/2017 - 12/2012
2	Retinal DehydrogenaseIBA 09/2016 - 01/2015
2	Tretinoin (Retinoic Acid)FDA LinkGeneric 01/2015 - 04/2011
2	LipofuscinIBA 01/2015 - 01/2013
2	plasminogen kringle 5IBA 01/2012 - 11/2005
2	Angiogenesis InhibitorsIBA 01/2012 - 06/2006
2	LDL Lipoproteins (beta Lipoproteins)IBA 09/2008 - 06/2008
2	Transforming Growth Factor beta (TGF-beta)IBA 06/2006 - 01/2005
1	OpsinsIBA 01/2022
1	EmulsionsIBA 12/2021
1	Protein Isoforms (Isoforms)IBA 01/2021
1	LigandsIBA 01/2021
1	interstitial retinol-binding proteinIBA 01/2021
1	Cytoplasmic and Nuclear Receptors (Nuclear Receptors)IBA 01/2021
1	Cyclin D1IBA 11/2020
1	Sincalide FDA Link 11/2020
1	Bromodeoxyuridine (BrdU)IBA 01/2020
1	AmidesIBA 01/2020
1	EndocannabinoidsIBA 01/2020
1	palmidrolIBA 01/2020
1	9-cis-retinalIBA 01/2020
1	CytokinesIBA 01/2020
1	Actins (F Actin)IBA 01/2020
1	C-Reactive ProteinIBA 01/2020
1	Reactive Oxygen Species (Oxygen Radicals)IBA 10/2019
1	sortilinIBA 01/2019
1	Antineoplastic Agents (Antineoplastics)IBA 01/2019

Therapy/Procedure

6	Therapeutics 01/2022 - 10/2010
5	Lasers (Laser) 12/2021 - 09/2012
4	Intravitreal Injections 01/2017 - 10/2010
2	Topical Administration 12/2021 - 01/2018
2	Injections 01/2020 - 01/2016
1	Oral Administration 12/2021
1	Transplantation 11/2020